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Corresponding author : Olakunle James Onaolapo, MBBS, MSc, PhD, Reader (Associate Professor), Department of Pharmacology, Ladoke Akintola University of Technology, College of Health Sciences, P.M.B 4000, Ogbomosho 234, Oyo, Nigeria

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Moreover, Sirt1 can regulate the viability of NIH3T3 cells and neurons following OGD/R injury in vitro via Shh signaling [13, 24]

Particularly, the induced depletion of GSH in organs of adult animals was greater than previously observed depletions using pharmacologic approaches 19